Showing posts with label scientists. Show all posts
Showing posts with label scientists. Show all posts
Scientists Explain How Vitamin D and Omega 3 Fats Synergistically Prevent Alzheimer’s Disease
Tuesday, March 11, 2014
A group of scientists have published the findings from their research in the Journal of Alzheimer’s Disease that has pinpointed how vitamin D3 and omega-3 fatty acids may enhance the immune systems ability to clear the brain of amyloid plaques. Researchers identified key genes and signaling networks regulated by vitamin D3 and the omega-3 fatty acid DHA (docosahexaenoic acid) that may help control inflammation and improve plaque clearance.
Vitamin D3 and DHA boost immune response to help prevent amyloid protein tangles
Prior studies have identified the loss of normal ability to break down amyloid proteins before they develop into tangles or plaques as a key process in the development of the memory-robbing disease. Lead study author, Dr. Milan Fiala from the David Geffen School of Medicine at UCLA commented “Our new study sheds further light on a possible role for nutritional substances such as vitamin D3 and omega-3 in boosting immunity to help fight Alzheimers.”
To perform their study, scientists drew blood samples from both Alzheimers patients and healthy controls and then isolated critical immune cells called macrophages from the blood. Macrophages are responsible for splicing the amyloid proteins before they can aggregate around the nerve synapse, effectively stifling electrical and chemical transmissions throughout the brain. Scientists then incubated the immune cells with amyloid-beta and added either an active form of vitamin D3 or the omega-3 fatty acid DHA to gauge effectiveness on inflammation and amyloid-beta absorption.
Supplement daily with Vitamin D3 and Omega-3 Fats to Slash Alzheimer’s Disease Risk
The researchers determined that vitamin D3 and DHA greatly improved the clearance of amyloid-beta by macrophages in patients with Alzheimer’s disease, and found subtleties in the effects the two substances had on the expression of inflammatory genes. The study team concluded “We may find that we need to caully balance supplementation with vitamin D3 and omega-3 fatty acids, depending on each patient in order to help promote efficient clearing of amyloid-beta…. this is a first step in understanding what form and in which patients these nutrition substances might work best."
The study team observed that each nutrient (vitamin D and DHA) utilized different receptors and common signaling pathways to prevent amyloid protein aggregation leading to disease. Optimizing vitamin D blood saturation levels and supplementing with a molecularly distilled DHA omega-3 formulation can provide critical support in helping the brain to properly clear amyloid metabolic byproducts and help prevent Alzheimer’s dementia.
Indian scientists find syringes without pain
Saturday, January 18, 2014
Indian scientists managed to find a way without using needles to vaccinate at all.
Scientists at Kings College London for the first time demonstrated their ability to provide life-dried vaccine into the skin without the traditional needle and found this technique is strong enough to activate specific immune cells in the skin.
The technical advancements offer a potential solution to the challenge of providing a live vaccine to some resource-limited countries globally, including India, without the need for refrigeration. A cheaper alternative to syringes, will also eliminate the risk of contamination of needles and pain-free.
"We have found that it is possible to maintain the effectiveness of live vaccines by means of drying the sugar and apply it on the skin by using a micro needle. We also discovered the role of certain cells in the skin that acts as a monitoring system," said Dr. Linda Klavinskis of King College told the Times of India.
This latest discovery involves a silicone mold to make micro needles made of sugar that can be dissolved when inserted into the skin.
Scientists at Kings College London for the first time demonstrated their ability to provide life-dried vaccine into the skin without the traditional needle and found this technique is strong enough to activate specific immune cells in the skin.
The technical advancements offer a potential solution to the challenge of providing a live vaccine to some resource-limited countries globally, including India, without the need for refrigeration. A cheaper alternative to syringes, will also eliminate the risk of contamination of needles and pain-free.
"We have found that it is possible to maintain the effectiveness of live vaccines by means of drying the sugar and apply it on the skin by using a micro needle. We also discovered the role of certain cells in the skin that acts as a monitoring system," said Dr. Linda Klavinskis of King College told the Times of India.
This latest discovery involves a silicone mold to make micro needles made of sugar that can be dissolved when inserted into the skin.
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