Showing posts with label risks. Show all posts
Showing posts with label risks. Show all posts

C3G From Grapes and Berries Lower Cancer and Chronic Disease Risks

Friday, May 2, 2014

The reddish and purple pigments that give many fruits, vegetables and berries their appealing color continue to shine as super functional nutrients that help prevent disease. The journal Molecular Cancer found that a special anthocyanin found in the skins of deeply colored vegetables and berries known as Cyanidin-3-glucoside (C3G) is a powerful antioxidant that can sacrifice itself to blunt the effect of health-damaging free radicals. 

Grapes, blueberries and black currants provide a potent source of C3G anthocyanins. Extensive scientific research is uncovering the specific mechanism that this nutrient exerts on our genes as a potent antioxidant and anti-inflammatory agent. C3G is shown to protect against many deadly age-related conditions including cancer, heart disease and metabolic syndrome.

C3G From Grapes Protects DNA Genetic Strands to Prevent Cancer
As improved techniques evolve that are capable of revealing the efficacy of specific compounds at the molecular and genetic level, C3G is beginning to shine as a potent influence on DNA strands that effect the production of free radicals. Researchers have found that this natural nutrient is able to prevent the formation of new free radicals and can neutralize the damaging effect of those already formed.

A high intake of fruits and vegetables is associated with a reduced incidence of cancer, largely due to polyphenols in the anthocyanin family including C3G. The result of a study published in Nutrition and Cancer provides insight into the powerful protective mechanism exhibited by anthocyanins toward developing cancer cells. C3G was shown to inhibit the action of special oncogenes (genes that lead to cancer formation), known to be the first stage in tumor genesis.

Further research identifies the link between C3G and suppression of the master inflammatory switch called NF-kB. Inflammation is a leading cause for cancer initiation and this functional compound has been shown to sacrifice itself as it inhibits the effect of NF-kB to prevent the formation of many tumor types.

C3G From Berries Fights Free Radicals to Avert Heart Disease
C3G is also an important player in preventing heart disease and the events that lead to a potentially fatal heart attack. Nitrogen-based free radicals are known to attack the inner endothelial lining of the coronary arteries, causing the surface to become resistant to the continual demands necessary to react quickly to changes in blood pressure. C3G neutralizes the effect of these damaging free radicals and helps to restore the normal elastic integrity of the delicate arteries that supply blood to the heart.

Results from the European EPIC study show that eating at least 8 servings of fresh fruits and vegetables each day can lower the risk of all-cause mortality by 22%. Anthocyanins such as C3G are one example of essential nutritional compounds found in natural foods that have been identified with a specific action shown to lower the risk of chronic disease. Health conscious individuals will want to ensure they eat at least 10 daily servings of vegetables and fruits (especially berries highly concentrated in C3G) to ward off many of the common diseases associated with aging.
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Eating Tree Nuts Lowers Chronic Disease Risks and Assists Successful Weight Loss

Monday, March 24, 2014


Consumption of nuts has been largely maligned by mainstream health professionals and the media for decades due to the high calorie and fat content. As we enter an era of enlightened understanding about the role of dietary fats and macronutrients in the promotion or degradation of health and weight management, forward-thinking scientists and practitioners rely on extensive research demonstrating the importance of healthy fats in their natural state to prevent heart disease, cancerand neurodegenerative conditions.

Researchers publishing the result of their work in the Journal of the American College of Nutrition have found that eating tree nuts (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) was associated with higher levels of high-density lipoprotein-cholesterol (good HDL cholesterol) and lower levels of C-reactive protein, a marker for inflammation which can lead to a variety of chronic diseases including heart disease.

Tree Nuts Shown to Lower Chronic Disease Risk and Helps Prevent Obesity
Lead study author, Dr. Carol O’Neil from the Louisiana State University Agricultural Center also observed“One of the more interesting findings was the fact that tree nut consumers had lower body weight, as well as lower body mass index (BMI) and waist circumference compared to non-consumers.” The scientists determined that those consuming tree nuts as part of their regular diet averaged slightly over 4 pounds lower body weight or nearly one inch smaller waist circumference.

The study centered on a cohort of 13,292 men and women participating in the 1999-2004 National Health and Nutrition Examination Surveys. Tree nut consumers were defined as those individuals consuming more than one-quarter ounce each day as determined from 24-hour recall data and questionnaires.

Eat a Handful of Tree Nuts Each Day to Lower Chronic Disease Risk
Tree nut consumption was associated with a five percent lower incidence of metabolic syndrome, a group of risk factors known to increase the risk for coronary artery disease, stroke and type II diabetes. Researchers further noted that the nut-consuming group exhibited a lower prevalence of abdominal obesity, high blood pressure, high fasting glucose (blood sugar) levels and low high-density lipoprotein-cholesterol levels.

Tree nuts consist of largely monounsaturated fats that are known to promote heart health, and have been shown to be of critical importance for optimal brain function. Dr. O’Neil concluded“Tree nuts should be an integral part of a healthy diet and encouraged by health professionals.” Nutritionists recommend eating 1 ½ ounces each day of raw, unheated, non-salted tree nuts to lower chronic disease risk and assist weight management goals.
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Institute of Medicine Agrees Health IT Poses Risks to Safety Here Are Their Recommendations

Friday, March 7, 2014

A CAT scan. Wheres that big spleen?
Years ago, the Disease Management Care Blog ordered an abdominal CAT scan for one of its patients. The study was reassuringly normal except for the unexpected - and most likely benign - finding of an enlarged spleen. In the absence of any other worrisome findings, the interpreting radiologist recommended that another CAT scan should be done in six months to make sure it wasnt getting bigger. The patient agreed. The DMCB then fired up the electronic health record (EHR), scheduled the CAT scan order for six months, closed the encounter and moved onto the next patient.

Approximately one year later the patient returned for an appointment. Thats when it was discovered that the CAT scan had never been scheduled. The DMCB was later told that the EHR wasnt configured to schedule tests 6 months in advance.*

Its on behalf of patients like this and their physicians that the DMCB welcomes this Institute of Medicine report on Health IT and Patient Safety. It recognizes what most front-line EHR-using physicians have known for years:

"The evidence in the literature about the impact of health information technology (IT) on patient safety, as opposed to quality, is mixed but shows that the challenges... involve people and clinical implementation as much as the technology. The literature describes significant improvements in some aspects of care in health care institutions with mature health IT.  For example, the use of computerized prescribing and bar-coding systems has been shown to improve medication safety. But the generalizability of the literature across the health care system may be limited. While some studies suggest improvements in patient safety can be made, others have found no effect. Instances of health IT–associated harm have been reported. However, little published evidence could be found quantifying the magnitude of the risk." (bolding from the DMCB)

In other words, selective reporting involving best case scenarios fail to account for the reality that the old safety issues of a paper-based system are being displaced by new safety issues of an IT system and, whats worse, we dont know the extent of the problem.

Here are the IOMs (paraphrased) recommendations to Health and Human Services (HHS):

1. HHS, working with the EHR vendors, should develop a health IT surveillance plan.

2. HHS should foster the free exchange of information and address the "legal clauses" in contracts that shift liability from the vendors to the doctors (The AMA has erred to these as "hold harmless" clauses).

3. Data is needed that allows health IT users to publicly compare and share experiences among multiple vendors.

4. "A Health IT Safety Council" that assesses and monitor health IT safety should be established.

5. A public register of all health IT vendors should be established.

6. Its time to specify those processes that reduce risk and make the vendors adopt them.

7. Health IT related deaths, serious injuries and unsafe conditions need to be centrally reported.

8. An independent federal entity should be established that is empowered to any investigate deaths, injuries or unsafe conditions.

9. HHS should report annually on its progress.

10 More cross-disciplinary research is needed to improve the design, testing and use of health IT.

Bravo says the DMCB, bravo!



*many of the facts are changed, but you get the gist
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