Showing posts with label anti. Show all posts
Showing posts with label anti. Show all posts
Drinking anti depression medication while pregnant harm the baby
Tuesday, May 20, 2014
Drinking anti-depression medication while pregnant harm the baby - Pregnant women are prone to depression should be wary before taking anti-depression medication. One study found that taking anti-depression drugs are quite popular during pregnancy can increase the risk of children born with heart defects.
Professor Stephen Pilling explains that women who take antidepressants during pregnancy early risk of having a child with a heart defect until doubled.
So far, scientists and doctors believe that eating oat anti-depression during pregnancy will not be a problem for the fetus in the womb. But Pilling said that it should be changed and straightened again.
"Mothers should be aware that they are causing more than doubled the risk (if taking anti-depression medication). I do not think that in most cases, the risk is worth taking," said Pilling, as reported by the BBC.
Pilling explains that the babys risk of having heart problems at birth are two of the 100 births. Meanwhile, when the mother taking anti-depression medication, this risk increased to four out of 100 births. Pilling suggested that pregnant women who are depressed and do not rush taking anti-depression medication.
Professor Stephen Pilling explains that women who take antidepressants during pregnancy early risk of having a child with a heart defect until doubled.
So far, scientists and doctors believe that eating oat anti-depression during pregnancy will not be a problem for the fetus in the womb. But Pilling said that it should be changed and straightened again.
"Mothers should be aware that they are causing more than doubled the risk (if taking anti-depression medication). I do not think that in most cases, the risk is worth taking," said Pilling, as reported by the BBC.
Pilling explains that the babys risk of having heart problems at birth are two of the 100 births. Meanwhile, when the mother taking anti-depression medication, this risk increased to four out of 100 births. Pilling suggested that pregnant women who are depressed and do not rush taking anti-depression medication.
Resveratrol anti tumor properties
Thursday, May 8, 2014
Resveratrol is a naturally occurring dietary compound found in grapes, berries, and peanuts. This polyphenol protects plants against pathogens such as bacteria and fungi by inducing cell death in invading organisms. The compound was discovered in red wine in 1939 but by and large did not attract the attention of the scientific community. More recently, pre-clinical studies have revealed the many beneficial properties of resveratrol. These include antidiabetic, cardioprotective, and chemopreventive effects. The latter has been associated to resveratrol antioxidant and anti-inflammatory proprieties.
A number of studies show that resveratrol induces cell death in different types of cancers, both in humans and animal models. However, the potential anti-tumor effect of resveratrol is still little understood as the compound seems to induce cell death in a number of cancer cells whereas in others no effect is observed, even when massive doses of resveratrol are used. A phase I study on the pharmacokinetic properties of resveratrol as a potential cancer chemopreventive agent has concluded that consumption of high levels of resveratrol would be insufficient to provide the amounts of resveratrol needed to elicit its chemopreventive proprieties. Nevertheless, a few ongoing clinical trials investigate the effects of resveratrol on a number of diseases, including colon cancer.
More recently, the anti-tumor functions of resveratrol have been associated to p53, a protein responsible for suppressing tumor development in the body. p53 is one of the main blockers of the cell cycle, leading cells to the death row. A faulty p53 is unable to suppress cell growth, which ultimately results in tumor development. Indeed, studies have shown that p53 is either defective or simply absent in most cancers.
To investigate whether resveratrol anti-tumor effects, as observed in some cancer cell lines, depend on the status of the cells p53 gene, a group led by Dr Jerson L. Silva at the Universidade Federal do Rio de Janeiro, Brazil, tested the effects of resveratrol in H1299, a human non-small lung carcinoma cell line carrying only a partial fragment of the p53 gene and compared the results with MCF-7, A549, and H460, which are cancer cell lines carrying normal copies of p53. The study shows that although resveratrol affects the viability of all cancer cell lines, MCF-7, A549, and H460 are more sensitive to the effects of resveratrol than H1299. While MCF-7 cell lines die after exposure to resveratrol, H1299 remains resistant. Additional findings indicate that the toxic effect of resveratrol on MCF-7, A549, and H460 cell lines is mediated by p53.
The research group then went one step further and asked what would happen if a normal copy of p53 is added to the previously p53-defective H1299 cancer cell line. The results, published this week in PLOS ONE, show that introduction of a normal copy of p53 in H1299 turns the cell line sensitive to the anti-tumor effects of resveratrol, similarly to that observed in other cancer cell lines (MCF-7, A549, and H460). "Our findings may have potential applications in cancer cell lines that are under p53 control," says Dr Danielly Ferraz da Costa, the first author of the study. "Also, the introduction of the p53 gene in p53-defective tumors, followed by resveratrol treatment, may represent a novel and promising therapeutic approach in our fight against cancer," says the young author.
New study strong anti cancer properties of soybeans
Wednesday, May 7, 2014
First study to report that proteins found in soybeans, could inhibit growth of colon, liver and lung cancers, published in Food Research International
Soybean meal is a bi-product following oil extraction from soybean seeds. It is rich in protein, which usually makes up around 40% of the nutritional components of the seeds and dependent on the line, and can also contain high oleic acid (a monounsaturated omega-9 fatty acid).
The study looked at the role soybeans could have in the prevention of cancer. Using a variety of soybean lines which were high in oleic acid and protein, the researchers looked to monitor bioactivity between the peptides derived from the meals of soybean and various types of human cancer cells.
The study showed that peptides derived from soybean meal significantly inhibited cell growth by 73% for colon cancer, 70% for liver cancer and 68% for lung cancer cells using human cell lines. This shows that the selected high oleic acid soybean lines could have a potential nutraceutical affect in helping to reduce the growth of several types of cancer cells.
Curcumin is a Powerful Anti Cancer Agent
Sunday, March 9, 2014
(Article first published as This Indian Spice Packs a Powerful Anti-Cancer Punch on Technorati.)
The spice can no longer be considered an herbal remedy as it has demonstrated efficacy in more than 240 peer reviewed research studies over the past year alone. Scientists continue to provide conclusive evidence that indicates all health-minded adults should include curcumin as part of their regular diet.
Curcumin Influences Gene Expression That Leads to Cancer
Publishing in the AAPS Journal, researchers found that curcumin is an inexpensive natural compound that fights cancer at its root cause by derailing the initiation phase of ten different pathways used by the disease to multiply and spread throughout the body. Curcumin has also been shown to interfere with the production of advanced glycation end products that promote the accumulation of dangerous inflammatory byproducts that lead to cancerous mutations.
Curcumin Shown to Trigger Natural Cell Death to Prevent Cancer
Curcumin is a potent agent in the fight against colon cancer, an insidious form of the disease that ranks second among cancer deaths taking the lives of more than 50,000 Americans each year. The Journal of Interferon and Cytokine Research provides evidence that curcumin slows the progression from colon polyp to cancerous growth by damping the pro-inflammatory cytokine called NF-kB. This action halts the development of cancer cells before they can become detectable tumors.
An extensive library of research underscores the importance of curcumin as an anti-cancer agent. As the second leading cause of death, cancer will affect 1 in 3 women and half of all men during their lifetime. Any natural compound that can help to lower these statistics should be embraced by traditional and alternative medical institutions alike. Nutritionists recommend supplementing with 250 to 400 mg of curcumin twice daily with meals to provide optimal cancer protection.
Resveratrol Provides Anti Aging Benefits and Helps Prevent Heart Disease
Sunday, February 9, 2014
Resveratrol has been a popular buzz word around the alternative health community for more than a decade, touted for its anti-aging properties and potent antioxidant and anti-inflammatory actions at the cellular level. Found in high concentrations most commonly in the skin of red grapes and in many red wines, resveratrol is thought to mimic the positive health benefits associated with calorie restriction by up-regulating longevity genes known as SIRT’s.
Scientists from the Harvard Medical School have publishedthe result of their work in the journal, Cell Biology that demonstrates how resveratrol provides metabolic benefits as a result of directly influencing the expression of genes that affect longevity. This research confirms conclusively for the first time that the metabolic benefits of the red wine ingredient disappear in mice that lack the famed longevity gene SIRT1.
Resveratrol Directly Influences Genetic Expression to Increase Lifespan
Resveratrol, commonly erred to as a ‘dirty molecule’, has gained notoriety for its unique ability to influence or alter the genetic expression of the SIRT family of longevity genes. Researchers have discovered that the naturally occurring ingredient has other effects; it influences dozens of other proteins critical to essential metabolic functions, and some evidence had pointed to the importance of another well-known gene(called AMPK) for resveratrols cellular benefits.
Researchers using a mouse model determined that resveratrol did not affect a group of mice that were genetically bred to ‘knock-out’ the SIRT gene (mice are commonly used for this type of study as they exhibit similar metabolic traits with humans). This confirmed that the grape-derived compound directly alters longevity expression in a dose dependent manner. Higher concentrations of resveratrol were found to increase the degree of genetic influence exhibited by resveratrol supplementation.
Resveratrol Lowers Systemic Inflammation to Reduce Heart Disease Risk
Further evidence documenting the importance of resveratrol to human health is provided by researchers publishing in the American Journal of Cardiology. Scientists found that cardiac patients supplemented for a period of one year with the red nutrient lowered multiple markers of inflammation (including CRP, C-reactive protein) by 26 percent, as well as reduced clotting factors associated with stroke. The researchers for this study used low doses of resveratrol (8 mg for the first six months and 16 mg for the next six months) to achieve these results.
A vocal group of naysayers constantly degrade the ever-growing evidence to support the importance of resveratrol to human wellbeing. There is little left to dispute, as researchers are regularly demonstrating that small amounts of resveratrol taken from diet or supplementation can benefit overall wellness and cardiovascular diseases by lowering levels of inflammation, providing antioxidant support and directly altering genetic expression to extend our healthy lifespan.
Vitamins and Supplements That Help With Anti Aging Care
Friday, December 27, 2013
A common question asked by many health conscious people is whether it is necessary to take a multi-vitamin or dietary supplement each day. The real simple answer depends on the quality of your diet. The human body has a certain requirement for all known vitamins and minerals which have been conveniently categorized as Recommended Daily Allowances (RDA by the FDA). These minimal requirements for vitamins and minerals were developed half a century ago to make public the smallest amount of each substance required to prevent diseases which were associated with an RDA deficiency. Current research is continually proving that the RDA specifications are not always the optimal dose necessary to prevent vibrant health into old age.
To supplement or not supplement, that is the question. Most natural health specialists believe that supplementation is required for optimal health, under the correct circumstances. To begin, there is no substitute for a good quality diet composed of raw vegetables (organic where possible), minimal fruits, lean protein, seeds, nuts and legumes. This should be the core of your diet, with foods eaten raw being 85% of total calories, and lean animal protein composing a maximum of 10%. This leaves no room for the empty calories derived from sweets, candies, refined wheat products or processed foods of any type. The types of food contain virtually no nutrients and lead to the epidemic growth of obesity and many lifestyle diseases (heart disease, cancer, stroke and dementia). This type of healthy diet will provide your body with virtually all of the known RDA nutrients. Even more important, there are other as yet unknown micro-nutrients in whole foods when eaten raw (cooking can damage or destroy many of the essential enzymes contained in many food items) which have yet to be discovered. It is clear that there is a synergy between all of the nutrients contained in these unprocessed foods which are essential to our body.
The human body has an amazing capacity to process the nutrition from the foods we eat, and an even higher capacity to protect us when we routinely take in lower than necessary amounts of the vitamins and minerals required to enable all the chemical and electrical reactions which we call life. The body has many backup mechanisms which it uses to allow us to survive a nutrient deficiency, but eventually over the course of years and decades it is no longer able to compensate. We are sent signals that there is a pending problem. We see them as lifes little aches and pains, indigestion and headaches. We ignore the problem, and then finally go to see a medical professional for a quick fix. We are given a pill, and go away thinking all will be well. But the problem has only been masked and continues to develop, as we have done nothing to correct the root cause.
We know that, regardless of the type of diet we eat, it is necessary to compliment our nutrient intake with some degree of dietary aid. Many people know this, which the reason nearly 70% of adults indicate they are taking a one a day vitamin supplement each day. While the thought is admirable, the effect on nutrition is negligible from this type of supplement. The problem is that the typical multi-vitamin is of very low quality and is made of synthetic components which the body has difficulty using. Stay away from any vitamin which is solid and made from compressed ingredients. These pills are of little use to the body, and due to the poor quality of the raw chemicals used will have no positive effect, and may actually cause harm. A much better choice is a natural vitamin supplement which will always come in a vegetarian capsule. And quality vitamins take up space, so you will probably need to take 6 - 12 of them spaced out through the day. You will notice that the RDA amounts will be well over 100%... this is a sign that the maker has done research which indicates they are including the optimal dose, and not the meager RDA amount. Read the label, and look for naturally sourced ingredients and be sure the manufacturer has a good reputation. A little research in this area will go a long way in something as important as your health.
Recently we have been provided solid science to back up the theory that dietary supplementation through our lives can yield powerful results in disease prevention as we age. Researchers have published the results of feeding an anti-aging cocktail to mice (mice are perfect test subjects as they have genetically similar pathways to humans), and made the observation: "complex dietary cocktails can powerfully ameliorate biomarkers of aging and modulate mechanisms considered ultimate goals for aging interventions." The cocktail consisted of essential vitamins and minerals and a handful of recognized extracts (carnitine, carnosine, resveratrol, COQ10, ginko, Omega-3s and green tea extracts). All components were provided in optimal doses. By comparing a group of supplemented mice to a set who received no intervention, the researchers were able to determine that the mice who consumed the cocktail showed a 50% reduction in the critical biomarkers which scientists use to gauge cellular aging. Although the mice did not live longer than the non-supplemented mice (only Calorie restriction has been documented to extend life), the supplemented mice suffered much less from disease, and had more energy for an extended period.
While there is no substitute for a good healthy diet of raw unprocessed foods, we know that most people require additional support to live a disease-free life. Proper selection of a dietary supplement is essential. Additionally, some people may need further specific dietary aids, depending on health conditions. Diabetes, heart disease and cancer all require a special regimen of supplementation which is beyond the daily multi-vitamin. It is important to research your needs based on health concerns, and avoid the barrage of lifestyle pharmaceuticals which do little to create vibrant health on a long term basis.
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