Showing posts with label system. Show all posts
Showing posts with label system. Show all posts

Exercise Could Fortify Immune System Against Future Cancers

Thursday, May 8, 2014



Researchers may soon be able to add yet another item to the list of exercises well-documented health benefits: A preliminary study suggests that when cancer survivors exercise for several weeks after they finish chemotherapy, their immune systems remodel themselves to become more effective, potentially fending off future incidents of cancer. The finding may help explain why exercise can significantly reduce the chances of secondary cancers in survivors or reduce the chances of cancer altogether in people who have never had the disease.

Laura Bilek, Graham Sharp, and Geoffrey Thiele, all of the University of Nebraska Medical Center, and Daniel Shackelford, Colin Quinn, and Carole Schneider, all of Rocky Mountain Cancer Rehabilitation Institute, analyzed T cells in the blood of cancer survivors before and after a 12-week exercise program. They found that a significant portion of these immune cells converted from a senescent form, which isnt as effective at combating disease, to a naïve form, ready to fight cancer and infections.

Their poster presentation entitled, "Effect of Exercise on T Cells in Cancer Survivors," will be discussed at The Integrative Biology of Exercise VI meeting being held October 10-13 at the Westin Westminster Hotel in Westminster, CO. This popular meeting is a collaborative effort between the American Physiological Society, the American College of Sports Medicine and the Canadian Society for Exercise Physiology. The conference is supported in part by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, an institute of the National Institutes of Health, GlaxoSmithKline, Inc., Stealth Peptides, Inc., and Seahorse Biosciences.

Exercise and Immunity

Study leader Laura Bilek explains that previous research had turned up a variety of positive associations between exercise and cancer -- notably, that exercise can reduce the risk of getting initial incidence of several different types of cancers, can often improve prognosis in cancer patients, and can reduce the risk of recurrence and secondary cancers survivors of some types of cancers. However, the mechanism behind these phenomena has been unknown.

Since other research has suggested that exercise can remodel the immune system, making it more effective at fighting disease in general, Bilek and her colleagues decided to investigate how exercise affects the immune system of cancer patients. Working with a group of 16 cancer survivors, all but one of who recently finished chemotherapy cancer treatment, the researchers focused on T cells, a type of immune cell that attacks a variety of infectious agents as well as cancer cells. After chemotherapy, previous research had shown that the majority of T cells become senescent, with a decreased ability to fight infections and cancers. However, Bilek says, rebuilding the population of responsive (naïve) T cells is critical for regaining normal immune function and cancer-fighting ability.

The researchers first took blood samples from each of the volunteers to examine how many senescent and naïve T cells each had. Then, these study subjects were all enrolled into 12-week exercise programs at the Rocky Mountain Cancer Rehabilitation Institute. All programs were individualized for the study participants, incorporating elements of cardiovascular exercise, strength and endurance training, and exercises for flexibility, posture, and balance, with extra emphasis in areas where participants were weak.

After the 12-week program, the researchers drew a second blood sample from each volunteer and ran the same T cell analysis.

Another Reason to Work Out Results showed that the ratio of senescent to naïve T cells changed favorably in the majority of participants, with most of the study subjects regaining greater numbers of the naïve variety.

"What were suggesting is that with exercise, you might be getting rid of T cells that arent helpful and making room for T cells that might be helpful," Bilek says.

She adds that this finding highlights the importance of exercise for all, including those with cancer and cancer survivors. These two populations might benefit especially from the heightened "cancer surveillance" -- the ability of the immune system to seek out and destroy budding cancers -- that this study suggests exercise brings, Bilek explains.

"Theres a litany of positive benefits from exercise," Bilek says. "If exercise indeed strengthens the immune system and potentially improves cancer surveillance, its one more thing we should educate patients about as a reason they should schedule regular activity throughout their day and make it a priority in their lives."

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How The System Of Human Body works

Saturday, April 26, 2014

Have you ever wondered about how the human body works? Many of us are born, live, and grow old, without even knowing how our body works and we never ever really try to know. Our body is an amazing creation. Knowing about our body, and how it works, can help you maintain a strong, healthy body and live a better life. 

The human body is like a fully automatic complex machine, with many little parts that work by themselves or with other parts to perform specific functions. Sometimes, it seems like our body has a mind of its own and it embarrasses you. So it’s important to know your body so you can recognize what is normal body behavior and what is not. If there is a problem with how your body works, by recognizing that there is a problem, you can take steps to fix it or get help.
The Amazing Human Body
Your body is comprised of tiny microscopic cells. Your body is made up of trillions of them. That is more than 1,000,000,000,000 cells! Cells are so small you cannot see them without a microscope. Cells are very important as they produce energy required for daily activities, or hold the coded instructions for everything from the color of your hair to whether you have freckles or not. Cells differentiate from each other to perform different, important tasks within the body. For example, some cells might become brain cells while others make bone, and red blood cells carry oxygen throughout the body, while white blood cells fight infection.

When a group of cells work together to perform a specific function, they are called tissue. There are four types of tissue within the body. The first, epithelial tissue protects the body and the organs by forming a protective outer layer. The skin, which is an example of epithelial tissue, is the first line of defense against infections. 

Nerve tissue carries messages from the brain to the rest of your body by sending electrical impulses. The electrical impulses tell the muscles when to contract and affect everything from the beating of your heart to the wiggling of your toes. 

Muscle tissue functions in movement because the muscle cells contract, shorten and relax. Muscle cells know when to contract or shorten because they receive electrical signals from nerve tissue. 

Finally, connective tissue holds the body together, provides support, insulation, and protection. Bones, tendons, and ligaments are all examples of connective tissue.

When two or more types of tissues work together to perform any specific task it is called an organ. An organ system is formed when two or more organs work together to perform a larger task. The mouth, throat, stomach, large and small intestines, liver, pancreas, and gallbladder all work together, as the digestive system, to process the food we eat so that our cells can absorb the nutrients and convert it into energy. 

Like this, there are many systems in the body, such as the skeletal, muscular, circulatory, nervous, digestive, immune, respiratory, urinary, and reproductive systems and they all interact with each other every second of our lives. Without these systems, humans would not be able to grow, maintain life, and reproduce.

Every machine requires fuel to work efficiently, your body being a fully automatic machine runs entirely on minerals and water. As an incredibly powerful solvent in your body, the hydrogen molecules in pure water provide nutrients in the form of energy to your cells and remove discarded, used energy. Without regular replacement of the water in your body, the cells will die, and so will your body. Likewise, without replacing essential trace minerals systematically in the correct, water soluble, ionic form, the cells will malfunction, become weak and fatally diseased.

Calcium, magnesium, phosphorus, potassium, and sodium are the five essential or major minerals for your body. Other important trace elements consist of chromium, copper, iodine, iron, manganese, and zinc. Additionally, selenium plays a key role in the maintenance of good health. Other trace elements like sulphur, nickel, cobalt, fluorine, oxygen, carbon, hydrogen, and nitrogen also have a part to play in your wellbeing. The human body depends upon 84 of the known 106 elements to maintain optimum health, many more than are now recognized.

Your body can do amazing things if it has the proper fuelo materials. For example, your body can grow, repair and heal itself if you provide it with essential nutrition and proper physical exercise. Vitamins are a major component of essential nutrition. Your body requires certain vitamins to function correctly. Without them, your body simply does not work properly.

Essential Vitamins
Essential vitamins are those that your body needs to get from foods because it is not able to make them on its own. There are 13 vitamins that are considered essential for proper body function. These include the B-vitamins and vitamins A, C, D, E and K. The B vitamins are thiamine, riboflavin, niacin, pantothenic acid, biotin, vitamin B6, vitamin B12 and folate. Each of the essential vitamins is used by your body for different processes and help with different systems, including your immune system, nervous system, and cardiovascular system.


Sources
Vitamins are best absorbed by the body when they come from whole and natural food sources. Vitamin supplements are helpful but not a good substitute for your childs balanced diet. The USDA recommends a diet centered on fruits and vegetables with whole grains, lean meats and dairy products to serve your childs nutritional needs. Some good sources of Vitamins A through K are: milk, cheese, eggs, whole wheat, oatmeal, spinach, legumes, kale, meat, fish, citrus fruits, bell peppers, broccoli, tomatoes, peaches, cantaloupe and mangoes.


Vitamin K plays an important role to strengthen the bones, avoid blood clotting and prevent hardening of arteries. Dark, leafy vegetables are good source of Vitamin K.

Vitamin C is an antioxidant vitamin that is believed to protect the brain from damage caused by Alzheimer. It helps you to tackle stress better and also protects you from common cold. A glass of Orange juice, citrus fruits, bell peppers, kiwifruit, papaya, broccoli, dark leafy greens and strawberries will provide you Vitamin C.

The antioxidant Vitamin E fights free radicals and reduces risk of heart disease, stroke and Alzheimer. Daily intake of nuts and seeds such as almonds and sunflower seeds will provide you Vitamin E.   

Potassium helps to maintain blood pressure. It also helps reduce your risk of stroke. Beans, potatoes, sweet potatoes, bananas, dried fruits, winter squash, cantaloupe, kiwi, orange juice, prune juice and avocados are good sources of Potassium. 
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Maternal anxiety during pregnancy affect the babys immune system

Wednesday, March 12, 2014

Maternal anxiety during pregnancy affect the babys immune system - Excessive anxiety can weaken the immune system. Apparently this does not apply to himself alone, but also on pregnant women and their fetuses. Research shows that the anxiety felt by the mother during pregnancy can affect a childs immune system.

Mothers who experience excessive anxiety weakening effect on the immune system when the baby is six months old, according to a study published in the journal Brain, behavior, and Immunity.

"We found that the anxiety experienced by the mother during pregnancy may decrease the effectiveness of immunization in children at the age of six months," said researcher Tom OConnor, a professor from the University of Rochester Medical Center, as reported by Fox News.

This conclusion is obtained after the researchers observed 210 pregnant women aged 20-34 years. They were asked to report the level of anxiety they experienced during the eight to 32 weeks of pregnancy. Researchers also examined saliva samples from the pregnant women to measure stress hormones.

After the researchers gave the hepatitis B vaccine in infants after they are born, at the age of three months and six months. At the age of six months babies begin to show the difference. Those who have mothers with high levels of anxiety showed an immune system response is lower.

Researchers have calculated other factors such as obesity of the mother during pregnancy, pregnancy complications, and mode of delivery. Even so, the effect on the babys anxiety began to disappear when the child is getting complete immunization dose.
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